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Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2949062

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

About this item

Full title

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

Publisher

London: Nature Publishing Group UK

Journal title

The pharmacogenomics journal, 2009-04, Vol.9 (2), p.127-136

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

hMATE1 (human multidrug and toxin compound extrusion-1; encoded by
SLC47A1
) is thought to have an important function in the renal and hepatic elimination of drugs, endogenous compounds and environmental toxins. The goals of this study were to identify genetic variants of hMATE1 and to determine their effects on hMATE1 transport function. We...

Alternative Titles

Full title

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2949062

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2949062

Other Identifiers

ISSN

1470-269X

E-ISSN

1473-1150

DOI

10.1038/tpj.2008.19

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