Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
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Author / Creator
Publisher
Alexandria, VA: American Diabetes Association
Journal title
Language
English
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Publisher
Alexandria, VA: American Diabetes Association
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Scope and Contents
Contents
Fibroblast growth factor 21 (FGF21) is a key mediator of fatty acid oxidation and lipid metabolism. Pharmacological doses of FGF21 improve glucose tolerance, lower serum free fatty acids, and lead to weight loss in obese mice. Surprisingly, however, FGF21 levels are elevated in obese ob/ob and db/db mice and correlate positively with BMI in humans....
Alternative Titles
Full title
Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2963536
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2963536
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db10-0193
