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DNA nanomechanics allows direct digital detection of complementary DNA and microRNA targets

DNA nanomechanics allows direct digital detection of complementary DNA and microRNA targets

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2966338

DNA nanomechanics allows direct digital detection of complementary DNA and microRNA targets

About this item

Full title

DNA nanomechanics allows direct digital detection of complementary DNA and microRNA targets

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2009-12, Vol.462 (7276), p.1075-1078

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A hint of nucleic acid
The ability to detect a specific DNA sequence at very low levels is invaluable in applications such as genetics and diagnostics. The best current technologies require amplification of the sample and/or labelling. In this study, a new method that avoids such sample preparation steps is described. It exploits a unique mechan...

Alternative Titles

Full title

DNA nanomechanics allows direct digital detection of complementary DNA and microRNA targets

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2966338

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2966338

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/nature08626

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