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Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2967734

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

About this item

Full title

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-10, Vol.467 (7318), p.977-981

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Early X-chromosome silencing
To ensure that female mammals do not have an excess of X-chromosome gene products, one of the two X chromosomes present in each cell is silenced. During embryogenesis, the imprinted form of this X-chromosome inactivation (XCI) process selectively silences the paternal X following the detection of
Xist
RNA expre...

Alternative Titles

Full title

Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2967734

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2967734

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09457

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