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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2970523

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

About this item

Full title

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2010-08, Vol.13 (8), p.951-957

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Marrs
et al
. show that the serine hydrolase α/β-hydrolase domain 6 (ABHD6) controls the accumulation and efficacy of the endocannabinoid 2-arachidonoylglycerol at cannabinoid receptors. ABHD6 is located post-synaptically and its selective inhibition permits the induction of cannabinoid receptor–dependent long-term depression by otherwise sub...

Alternative Titles

Full title

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2970523

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2970523

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.2601

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