O-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding
O-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding
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Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Alpha-dystroglycan (α-DG) is a cell-surface glycoprotein that acts as a receptor for both extracellular matrix proteins containing laminin-G domains and certain arenaviruses. Receptor binding is thought to be mediated by a posttranslational modification, and defective binding with laminin underlies a subclass of congenital muscular dystrophy. Using...
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Full title
O-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2978000
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2978000
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1180512
