Lentivirus-mediated Reprogramming of Somatic Cells in the Absence of Transgenic Transcription Factor...
Lentivirus-mediated Reprogramming of Somatic Cells in the Absence of Transgenic Transcription Factors
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Retroviral vectors remain the most efficient and widely applied system for induction of pluripotency. However, mutagenic effects have been documented in both laboratory and clinical gene therapy studies, principally as a result of dysregulated host gene expression in the proximity of defined integration sites. Here, we report that cells with charac...
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Full title
Lentivirus-mediated Reprogramming of Somatic Cells in the Absence of Transgenic Transcription Factors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2997595
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2997595
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2010.231
