Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not requ...
Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons
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Author / Creator
Donato, Jr, Jose , Cravo, Roberta M , Frazão, Renata , Gautron, Laurent , Scott, Michael M , Lachey, Jennifer , Castro, Inar A , Margatho, Lisandra O , Lee, Syann , Lee, Charlotte , Richardson, James A , Friedman, Jeffrey , Chua, Jr, Streamson , Coppari, Roberto , Zigman, Jeffrey M , Elmquist, Joel K and Elias, Carol F
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Studies in humans and rodents indicate that a minimum amount of stored energy is required for normal pubertal development. The adipocyte-derived hormone leptin is a key metabolic signal to the neuroendocrine reproductive axis. Humans and mice lacking leptin or the leptin receptor (LepR) (ob/ob and db/db mice, respectively) are infertile and fail to...
Alternative Titles
Full title
Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3007164
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3007164
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI45106
