Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6
Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Recombinant adeno-associated viral (rAAV) vector-mediated gene transfer represents a promising approach for many diseases. However, the applicability of rAAV vectors has long been hindered by the small (~4.8 kb) DNA packaging capacity. This limitation can hamper the packaging and delivery of critical regulatory elements and/or larger coding sequenc...
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Full title
Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3017440
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3017440
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2010.205
