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TDP‐43 regulates its mRNA levels through a negative feedback loop

TDP‐43 regulates its mRNA levels through a negative feedback loop

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3025456

TDP‐43 regulates its mRNA levels through a negative feedback loop

About this item

Full title

TDP‐43 regulates its mRNA levels through a negative feedback loop

Publisher

London: Nature Publishing Group UK

Journal title

The EMBO journal, 2011-01, Vol.30 (2), p.277-288

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

TAR DNA‐binding protein (TDP‐43) is an evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) involved in RNA processing, whose abnormal cellular distribution and post‐translational modification are key markers of certain neurodegenerative diseases, such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration. We ge...

Alternative Titles

Full title

TDP‐43 regulates its mRNA levels through a negative feedback loop

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3025456

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3025456

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2010.310

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