Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina
Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina
About this item
Full title
Author / Creator
Petrs-Silva, Hilda , Dinculescu, Astra , Li, Qiuhong , Deng, Wen-Tao , Pang, Ji-jing , Min, Seok-Hong , Chiodo, Vince , Neeley, Andy W , Govindasamy, Lakshmanan , Bennett, Antonette , Agbandje-McKenna, Mavis , Zhong, Li , Li, Baozheng , Jayandharan, Giridhara R , Srivastava, Arun , Lewin, Alfred S and Hauswirth, William W
Publisher
United States: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
Vectors based on adeno-associated virus serotype 2 (AAV2) have been used extensively in many gene-delivery applications, including several successful clinical trials for one type of Leber congenital amaurosis in the retina. Many studies have focused on improving AAV2 transduction efficiency and cellular specificity by genetically engineering its ca...
Alternative Titles
Full title
Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3034844
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3034844
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2010.234
