Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tumour cells release an abundance of microvesicles containing a selected set of proteins and RNAs. Here, we show that tumour microvesicles also carry DNA, which reflects the genetic status of the tumour, including amplification of the oncogene
c-Myc
. We also find amplified
c-Myc
in serum microvesicles from tumour-bearing mice. Further,...
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Full title
Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3040683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3040683
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms1180
