Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry
Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Immunohistochemistry is the most common method for companion diagnostic testing in breast cancer. The readings for estrogen receptor, progesterone receptor, and Her2 directly affect prescription of critical therapies. However, immunohistochemistry is highly sensitive to innumerable pre-analytic variables that result in loss of signal in these assay...
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Full title
Pre-analytic variables and phospho-specific antibodies: the Achilles heel of immunohistochemistry
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3046444
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3046444
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ISSN
1465-542X,1465-5411
E-ISSN
1465-542X
DOI
10.1186/bcr2782
