Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
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Author / Creator
Ressler, Kerry J. , Mercer, Kristina B. , Bradley, Bekh , Jovanovic, Tanja , Mahan, Amy , Kerley, Kimberly , Norrholm, Seth D. , Kilaru, Varun , Smith, Alicia K. , Myers, Amanda J. , Ramirez, Manuel , Engel, Anzhelika , Hammack, Sayamwong E. , Toufexis, Donna , Braas, Karen M. , Binder, Elisabeth B. and May, Victor
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pituitary adenylate cyclase-activating polypeptide (PACAP) is known to broadly regulate the cellular stress response. In contrast, it is unclear if the PACAP–PAC1 receptor pathway has a role in human psychological stress responses, such as post-traumatic stress disorder (PTSD). Here we find, in heavily traumatized subjects, a sex-specific associati...
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Full title
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3046811
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3046811
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09856
