HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
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Author / Creator
Kurosu, T , Ohga, N , Hida, Y , Maishi, N , Akiyama, K , Kakuguchi, W , Kuroshima, T , Kondo, M , Akino, T , Totsuka, Y , Shindoh, M , Higashino, F and Hida, K
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Background:
Tumour stromal cells differ from its normal counterpart. We have shown that tumour endothelial cells (TECs) isolated from tumour tissues are also abnormal. Furthermore, we found that mRNAs of vascular endothelial growth factor-A (VEGF-A) and cyclooxygenase-2 (COX-2) were upregulated in TECs. Vascular endothelial growth factor-A and C...
Alternative Titles
Full title
HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3048211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3048211
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2011.20
