Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in huma...
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
About this item
Full title
Author / Creator
Walmsley, Sarah R , Chilvers, Edwin R , Thompson, Alfred A , Vaughan, Kathryn , Marriott, Helen M , Parker, Lisa C , Shaw, Gary , Parmar, Selina , Schneider, Martin , Sabroe, Ian , Dockrell, David H , Milo, Marta , Taylor, Cormac T , Johnson, Randall S , Pugh, Christopher W , Ratcliffe, Peter J , Maxwell, Patrick H , Carmeliet, Peter and Whyte, Moira K B
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
The regulation of neutrophil lifespan by induction of apoptosis is critical for maintaining an effective host response and preventing excessive inflammation. The hypoxia-inducible factor (HIF) oxygen-sensing pathway has a major effect on the susceptibility of neutrophils to apoptosis, with a marked delay in cell death observed under hypoxic conditi...
Alternative Titles
Full title
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
Authors, Artists and Contributors
Author / Creator
Chilvers, Edwin R
Thompson, Alfred A
Vaughan, Kathryn
Marriott, Helen M
Parker, Lisa C
Shaw, Gary
Parmar, Selina
Schneider, Martin
Sabroe, Ian
Dockrell, David H
Milo, Marta
Taylor, Cormac T
Johnson, Randall S
Pugh, Christopher W
Ratcliffe, Peter J
Maxwell, Patrick H
Carmeliet, Peter
Whyte, Moira K B
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3049381
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3049381
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI43273
