Age-Dependent Effect of Apolipoprotein E4 on Functional Outcome after Controlled Cortical Impact in...
Age-Dependent Effect of Apolipoprotein E4 on Functional Outcome after Controlled Cortical Impact in Mice
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London, England: SAGE Publications
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Language
English
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London, England: SAGE Publications
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The apolipoprotein E4 (APOE4) gene leads to increased brain amyloid beta (Aβ) and poor outcome in adults with traumatic brain injury (TBI); however, its role in childhood TBI is controversial. We hypothesized that the transgenic expression of human APOE4 worsens the outcome after controlled cortical impact (CCI) in adult but not immature mice. Adul...
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Age-Dependent Effect of Apolipoprotein E4 on Functional Outcome after Controlled Cortical Impact in Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3049498
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3049498
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ISSN
0271-678X,1559-7016
E-ISSN
1559-7016
DOI
10.1038/jcbfm.2010.99
