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Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum mem...

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum mem...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3054032

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes

About this item

Full title

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (10), p.3976-3981

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The generation of the tubular network of the endoplasmic reticulum (ER) requires homotypic membrane fusion that is mediated by the dynamin-like, membrane-bound GTPase atlastin (ATL). Here, we have determined crystal structures of the cytosolic segment of human ATL1, which give insight into the mechanism of membrane fusion. The structures reveal a G...

Alternative Titles

Full title

Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3054032

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3054032

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1101643108

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