The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules
The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Understanding genomic organization in three dimensions may be one key to understanding gene regulation. Through the combination of an advanced version of chromosome conformation capture technology and an integrated modeling platform, the structure of the α-globin locus in cells where it is silent is compared to that in cells with high α-globin expr...
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Full title
The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3056208
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3056208
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.1936