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The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3056208

The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

About this item

Full title

The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2011-01, Vol.18 (1), p.107-114

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Understanding genomic organization in three dimensions may be one key to understanding gene regulation. Through the combination of an advanced version of chromosome conformation capture technology and an integrated modeling platform, the structure of the α-globin locus in cells where it is silent is compared to that in cells with high α-globin expr...

Alternative Titles

Full title

The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3056208

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3056208

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/nsmb.1936

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