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NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated...

NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_305695

NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

About this item

Full title

NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2000-05, Vol.19 (9), p.2015-2023

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Targeted disruption of the transcription factor
NKX2.3
gene in mice results in anatomical defects of intestine and secondary lymphoid organs. Here, we report that spleen and Peyer's patches of NKX2.3‐deficient mice are considerably reduced in size and lack the ordered tissue architecture. T and B cells are misplaced within the spleen and mese...

Alternative Titles

Full title

NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_305695

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_305695

Other Identifiers

ISSN

0261-4189,1460-2075

E-ISSN

1460-2075

DOI

10.1093/emboj/19.9.2015

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