Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic sil...
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A prostate cancer epigenome map reveals that genes are suppressed in clusters through long-range epigenetic silencing (LRES). Regions of LRES contain known tumour suppressors and miRNAs, and may expand to neighbouring genes during tumour progression.
Silencing of individual genes can occur by genetic and epigenetic processes during carcinogenesi...
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Full title
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3058354
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3058354
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2023
