RIP3 mediates the embryonic lethality of caspase-8-deficient mice
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Caspase-8 joins RIPK at the death
Caspase-8 mediates apoptosis induced by 'death receptors' on the cell's surface. At the same time, it is able to prevent receptor interacting protein kinase (RIPK)-dependent necrosis. Without caspase-8, mice die during embryonic development, but why this happens is not clear. Two groups show that this lethality...
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RIP3 mediates the embryonic lethality of caspase-8-deficient mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3060292
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3060292
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09857
