Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of...
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
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Author / Creator
Chae, Pil Seok , Rasmussen, Søren G F , Rana, Rohini R , Gotfryd, Kamil , Chandra, Richa , Goren, Michael A , Kruse, Andrew C , Nurva, Shailika , Loland, Claus J , Pierre, Yves , Drew, David , Popot, Jean-Luc , Picot, Daniel , Fox, Brian G , Guan, Lan , Gether, Ulrik , Byrne, Bernadette , Kobilka, Brian and Gellman, Samuel H
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Readily synthesized maltose–neopentyl glycol (MNG) amphiphiles are useful reagents for stabilizing, extracting and crystallizing a variety of integral membrane proteins and have favorable properties relative to conventional detergents.
The understanding of integral membrane protein (IMP) structure and function is hampered by the difficulty of ha...
Alternative Titles
Full title
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3063152
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3063152
Other Identifiers
ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.1526
