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MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transiti...

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transiti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3063863

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

About this item

Full title

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2011-03, Vol.30 (12), p.1449-1459

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Increased motility and invasiveness of pancreatic cancer cells are associated with epithelial to mesenchymal transition (EMT). Snai1 and Slug are zinc-finger transcription factors that trigger this process by repressing E-cadherin and enhancing vimentin and N-cadherin protein expression. However, the mechanisms that regulate this activation in panc...

Alternative Titles

Full title

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3063863

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3063863

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2010.526

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