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Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inh...

Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inh...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3065271

Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

About this item

Full title

Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

Publisher

London: Nature Publishing Group UK

Journal title

British journal of cancer, 2011-03, Vol.104 (6), p.1038-1048

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Background:
Pancreatic cancer (PC) harbours an activated point mutation (Kras
G12D
) in the Kras proto-oncogene that has been demonstrated to promote the development of PC.
Methods:
This study was designed to investigate the effect of the oncogenic Kras
G12D
allele on aggressiveness and metastatic potential of PC cells. We sile...

Alternative Titles

Full title

Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3065271

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3065271

Other Identifiers

ISSN

0007-0920

E-ISSN

1532-1827

DOI

10.1038/bjc.2011.31

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