Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inh...
Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin
About this item
Full title
Author / Creator
Rachagani, S , Senapati, S , Chakraborty, S , Ponnusamy, M P , Kumar, S , Smith, L M , Jain, M and Batra, S K
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background:
Pancreatic cancer (PC) harbours an activated point mutation (Kras
G12D
) in the Kras proto-oncogene that has been demonstrated to promote the development of PC.
Methods:
This study was designed to investigate the effect of the oncogenic Kras
G12D
allele on aggressiveness and metastatic potential of PC cells. We sile...
Alternative Titles
Full title
Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3065271
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3065271
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2011.31