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Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S pr...

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_306610

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes

About this item

Full title

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2000-08, Vol.19 (15), p.4144-4153

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

The 26S proteasome is a multisubunit protein‐ destroying machinery that degrades ubiquitin‐tagged proteins. To date only a single species of Rpn10, which possibly functions as a multiubiquitin chain‐binding subunit, has been identified in various organisms. Here we report that mouse Rpn10 mRNAs occur in at least five distinct forms, named Rpn10a to...

Alternative Titles

Full title

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_306610

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_306610

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1093/emboj/19.15.4144

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