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Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in mo...

Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in mo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3068609

Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study

About this item

Full title

Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study

Publisher

Bridgewater, NJ: EM Inc USA

Journal title

Clinical therapeutics, 2010-07, Vol.32 (7), p.1234-1251

Language

English

Formats

Publication information

Publisher

Bridgewater, NJ: EM Inc USA

More information

Scope and Contents

Contents

Abstract Background: Currently approved Alzheimer's disease (AD) treatments have been reported to provide symptomatic benefit, without proven impact on clinical progression. We hypothesized that the loss of initial therapeutic benefit over time may be mitigated by higher doses of a cholinesterase inhibitor. Objective: The aim of this study was to d...

Alternative Titles

Full title

Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3068609

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3068609

Other Identifiers

ISSN

0149-2918

E-ISSN

1879-114X

DOI

10.1016/j.clinthera.2010.06.019

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