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MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3074610

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

About this item

Full title

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2011-04, Vol.13 (4), p.423-433

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional targeting capabilities. Cellular export of miRNAs to HDL was demonstrated to be regulated by neutral s...

Alternative Titles

Full title

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3074610

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3074610

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb2210

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