Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease
Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
People with nonsyndromic congenital retinal nonattachment (NCRNA) are blind from birth. The authors show that NCRNA is caused by a deletion spanning a remote
cis
regulatory element upstream from
ATOH7
(
Math5
), a transcription factor gene required for retinal development. The deleted region is a conserved secondary transcriptiona...
Alternative Titles
Full title
Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3083485
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3083485
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2798
