Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Metastasis is a defining feature of malignant tumors and is the most common cause of cancer-related death, yet the genetics of metastasis are poorly understood. We used exome capture coupled with massively parallel sequencing to search for metastasis-related mutations in highly metastatic uveal melanomas of the eye. Inactivating somatic mutations w...
Alternative Titles
Full title
Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3087380
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3087380
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1194472
