Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
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Author / Creator
Liu, Guang-Hui , Barkho, Basam Z. , Ruiz, Sergio , Diep, Dinh , Qu, Jing , Yang, Sheng-Lian , Panopoulos, Athanasia D. , Suzuki, Keiichiro , Kurian, Leo , Walsh, Christopher , Thompson, James , Boue, Stephanie , Fung, Ho Lim , Sancho-Martinez, Ignacio , Zhang, Kun , Yates, John Yates and Belmonte, Juan Carlos Izpisua
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
An
in vitro
model of premature ageing
The premature ageing disorder Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic condition characterized by a rapid onset of signs associated with normal ageing, such as atherosclerosis and the degeneration of vascular smooth-muscle cells. Liu
et al
. report that the altered structure...
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Full title
Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3088088
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3088088
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09879
