DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Priming DNA for repair
When DNA damage introduces double-strand breaks, the ends formed must undergo processing to prepare them for repair. In related studies by the Sung and Kowalczykowski laboratories, this processing reaction has been replicated
in vitro
using yeast proteins. Processing minimally requires the activities of a helicase, a...
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DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3089589
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3089589
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09355
