Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes
Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes
About this item
Full title
Author / Creator
Fisher, D.L. , Mandart, E. and Dorée, M.
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
During
Xenopus
oocyte maturation, the Mos protein kinase is synthesized and activates the MAP kinase cascade. In this report, we demonstrate that the synthesis and activation of Mos are two separable processes. We find that Hsp90 function is required for activation and phosphorylation of Mos and full activation of the MAP kinase cascade. Once...
Alternative Titles
Full title
Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_310221
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_310221
Other Identifiers
ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/19.7.1516
