Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bon...
Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis
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Author / Creator
Publisher
England: ScholarOne
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Language
English
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Publisher
England: ScholarOne
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Scope and Contents
Contents
Inhibition of histone deacetylases (HDAC) has been shown to modulate gene expression and cytokine production after stimulation with several stimuli. In the present study, the antiinflammatory effect of a potent HDACi, ITF2357, was explored in different experimental models of arthritis. In addition, the bone protective effect of ITF2357 was investig...
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Full title
Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3105133
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3105133
Other Identifiers
ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2011.00058
