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Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose pro...

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose pro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3131508

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice

About this item

Full title

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Diabetologia, 2011-08, Vol.54 (8), p.2132-2142

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Aims/hypothesis
Obesity is strongly associated with the development of non-alcoholic fatty liver disease (NAFLD). The cytokine osteopontin (OPN) was recently shown to be involved in obesity-induced adipose tissue inflammation and reduced insulin response. Accumulating evidence links OPN to the pathogenesis of NAFLD. Here we aimed to identify the...

Alternative Titles

Full title

Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3131508

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3131508

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-011-2170-0

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