Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose pro...
Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
About this item
Full title
Author / Creator
Kiefer, F. W. , Neschen, S. , Pfau, B. , Legerer, B. , Neuhofer, A. , Kahle, M. , Hrabé de Angelis, M. , Schlederer, M. , Mair, M. , Kenner, L. , Plutzky, J. , Zeyda, M. and Stulnig, T. M.
Publisher
Berlin/Heidelberg: Springer-Verlag
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer-Verlag
Subjects
More information
Scope and Contents
Contents
Aims/hypothesis
Obesity is strongly associated with the development of non-alcoholic fatty liver disease (NAFLD). The cytokine osteopontin (OPN) was recently shown to be involved in obesity-induced adipose tissue inflammation and reduced insulin response. Accumulating evidence links OPN to the pathogenesis of NAFLD. Here we aimed to identify the...
Alternative Titles
Full title
Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3131508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3131508
Other Identifiers
ISSN
0012-186X
E-ISSN
1432-0428
DOI
10.1007/s00125-011-2170-0