Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology
Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The neurodevelopmental disorder Rett Syndrome (RTT) is caused by sporadic mutations in the transcriptional factor methyl CpG–binding protein 2 (MeCP2). The authors show that the loss of MeCP2 also occurs in glial cells in RTT brains. Moreover, in an
in vitro
coculture system, mutant astrocytes from a RTT mouse model affect the dendritic morph...
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Full title
Non–cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3134296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3134296
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.2275
