ChIP-Seq identification of weakly conserved heart enhancers
ChIP-Seq identification of weakly conserved heart enhancers
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Author / Creator
Blow, Matthew J , McCulley, David J , Li, Zirong , Zhang, Tao , Akiyama, Jennifer A , Holt, Amy , Plajzer-Frick, Ingrid , Shoukry, Malak , Wright, Crystal , Chen, Feng , Afzal, Veena , Bristow, James , Ren, Bing , Black, Brian L , Rubin, Edward M , Visel, Axel , Pennacchio, Len A and Joint Genome Institute (JGI)
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Len Pennacchio and colleagues used ChIP-Seq with the enhancer-associated protein p300 to identify 3,000 candidate cardiac transcriptional enhancers in embryonic mice at E11.5. Notably, most candidate heart enhancers at this time point are not deeply evolutionarily conserved.
Accurate control of tissue-specific gene expression plays a pivotal rol...
Alternative Titles
Full title
ChIP-Seq identification of weakly conserved heart enhancers
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3138496
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3138496
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.650
