Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-t...
Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
Inositol 1,4,5‐trisphosphate receptors (IP
3
Rs) are a family of intracellular Ca
2+
channels that exist as homo‐ or heterotetramers. In order to determine whether the N‐terminal ligand‐binding domain is in close physical proximity to the C‐terminal pore domain, we prepared microsomal membranes from COS‐7 cells expressing recombinant ty...
Alternative Titles
Full title
Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_313997
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_313997
Other Identifiers
ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/19.20.5450
