A yeast-based assay identifies drugs active against human mitochondrial disorders
A yeast-based assay identifies drugs active against human mitochondrial disorders
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Publisher
United States: National Acad Sciences
Journal title
Language
English
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Publisher
United States: National Acad Sciences
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Scope and Contents
Contents
Due to the lack of relevant animal models, development of effective treatments for human mitochondrial diseases has been limited. Here we establish a rapid, yeast-based assay to screen for drugs active against human inherited mitochondrial diseases affecting ATP synthase, in particular NARP (neuropathy, ataxia, and retinitis pigmentosa) syndrome. T...
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Full title
A yeast-based assay identifies drugs active against human mitochondrial disorders
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3141935
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3141935
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1101478108
