A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
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Author / Creator
Garcia-Gonzalo, Francesc R , Corbit, Kevin C , Sirerol-Piquer, María Salomé , Ramaswami, Gokul , Otto, Edgar A , Noriega, Thomas R , Seol, Allen D , Robinson, Jon F , Bennett, Christopher L , Josifova, Dragana J , García-Verdugo, José Manuel , Katsanis, Nicholas , Hildebrandt, Friedhelm and Reiter, Jeremy F
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Jeremy Reiter and colleagues show that Tctn1 is a component of a transition zone complex that regulates ciliogenesis and ciliary membrane composition. They also identify a likely causal mutation in
TCTN1
in two siblings with Joubert syndrome.
Mutations affecting ciliary components cause ciliopathies. As described here, we investigated Tect...
Alternative Titles
Full title
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3145011
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3145011
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.891
