Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Gavin Kelsey and colleagues report methylation landscapes in mouse oocytes, sperm and blastocysts. They find that the majority of methylated CpG islands in oocytes display incomplete demethylation in preimplantation embryos.
Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is essential to understand genomic impr...
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Full title
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3146050
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3146050
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.864