Cell type of origin influences the molecular and functional properties of mouse induced pluripotent...
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Polo
et al
. show that early-passage induced pluripotent stem cells retain an epigenetic memory of their cell type of origin. These epigenetic differences affect the cells’ differentiation potential and might be exploited to generate particular cell types of interest.
Induced pluripotent stem cells (iPSCs) have been derived from various so...
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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148605
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148605
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1667
