RhoA protects the mouse heart against ischemia/reperfusion injury
RhoA protects the mouse heart against ischemia/reperfusion injury
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
The small GTPase RhoA serves as a nodal point for signaling through hormones and mechanical stretch. However, the role of RhoA signaling in cardiac pathophysiology is poorly understood. To address this issue, we generated mice with cardiomyocyte-specific conditional expression of low levels of activated RhoA (CA-RhoA mice) and demonstrated that the...
Alternative Titles
Full title
RhoA protects the mouse heart against ischemia/reperfusion injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148727
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148727
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI44371