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RhoA protects the mouse heart against ischemia/reperfusion injury

RhoA protects the mouse heart against ischemia/reperfusion injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148727

RhoA protects the mouse heart against ischemia/reperfusion injury

About this item

Full title

RhoA protects the mouse heart against ischemia/reperfusion injury

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2011-08, Vol.121 (8), p.3269-3276

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The small GTPase RhoA serves as a nodal point for signaling through hormones and mechanical stretch. However, the role of RhoA signaling in cardiac pathophysiology is poorly understood. To address this issue, we generated mice with cardiomyocyte-specific conditional expression of low levels of activated RhoA (CA-RhoA mice) and demonstrated that the...

Alternative Titles

Full title

RhoA protects the mouse heart against ischemia/reperfusion injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148727

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3148727

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI44371

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