DMRT1 prevents female reprogramming in the postnatal mammalian testis
DMRT1 prevents female reprogramming in the postnatal mammalian testis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
DMRT1 loss is cue for sex swap
The presence or absence of the Y-chromosome gene
Sry
determines whether precursor cells differentiate into testicular Sertoli cells or ovarian granulosa cells in the mammalian fetus. Loss of the transcription factor FOXL2 in the adult ovary can lead to transdifferentiation of granulosa cells into Sertoli cell...
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Full title
DMRT1 prevents female reprogramming in the postnatal mammalian testis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3150961
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3150961
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10239
