GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Here, we report the identification of GIDE, a mitochondrially located E3 ubiquitin ligase. GIDE contains a C-terminal RING finger domain, which is mostly conserved with those of the lAP family members and is required for GIDE＇s E3 ligase activity. Overexpression of GIDE induces apoptosis via a pathway involving activation of caspases, since caspase...
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GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3156110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3156110
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2008.75
