Desmoglein 3–specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice
Desmoglein 3–specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Pemphigus vulgaris (PV) is a severe autoimmune disease involving blistering of the skin and mucous membranes. It is caused by autoantibodies against desmoglein 3 (Dsg3), an adhesion molecule critical for maintaining epithelial integrity in the skin, oral mucosa, and esophagus. Knowing the antigen targeted by the autoantibodies renders PV a valuable...
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Full title
Desmoglein 3–specific CD4+ T cells induce pemphigus vulgaris and interface dermatitis in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3163963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3163963
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI57379
