Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours
About this item
Full title
Author / Creator
Rajan, N , Elliott, R , Clewes, O , Mackay, A , Reis-Filho, J S , Burn, J , Langtry, J , Sieber-Blum, M , Lord, C J and Ashworth, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Individuals with germline mutations in the tumour-suppressor gene
CYLD
are at high risk of developing disfiguring cutaneous appendageal tumours, the defining tumour being the highly organised cylindroma. Here, we analysed
CYLD
mutant tumour genomes by array comparative genomic hybridisation and gene expression microarray analysis.
CY...
Alternative Titles
Full title
Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3175103
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3175103
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2011.133
