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Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic D...

Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic D...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188741

Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells

About this item

Full title

Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells

Publisher

United States: Elsevier Inc

Journal title

Molecular therapy, 2011-10, Vol.19 (10), p.1896-1904

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Current methods for eradicating clinically significant inhibitory antibodies to human factor VIII (hFVIII) in patients with hemophilia A rely on repeated delivery of high doses of factor concentrates for a minimum of many months. We hypothesize that tolerance can be induced more efficiently and reliably through hFVIII antigen presentation by tolero...

Alternative Titles

Full title

Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188741

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188741

Other Identifiers

ISSN

1525-0016

E-ISSN

1525-0024

DOI

10.1038/mt.2011.134

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