Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic D...
Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells
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United States: Elsevier Inc
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Language
English
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United States: Elsevier Inc
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Contents
Current methods for eradicating clinically significant inhibitory antibodies to human factor VIII (hFVIII) in patients with hemophilia A rely on repeated delivery of high doses of factor concentrates for a minimum of many months. We hypothesize that tolerance can be induced more efficiently and reliably through hFVIII antigen presentation by tolero...
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Full title
Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188741
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188741
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2011.134