CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzh...
CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease
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Author / Creator
Publisher
England: ScholarOne
Journal title
Language
English
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Publisher
England: ScholarOne
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Scope and Contents
Contents
The calcium homeostasis modulator 1 (CALHM1) gene codes for a novel cerebral calcium channel controlling intracellular calcium homeostasis and amyloid-β (Aβ) peptide metabolism, a key event in the etiology of Alzheimer's disease (AD). The P86L polymorphism in CALHM1 (rs2986017) initially was proposed to impair CALHM1 functionally and to lead to an...
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Full title
CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188873
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3188873
Other Identifiers
ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2011.00154
