Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
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Author / Creator
Li, Heng , Tong, Shuilong , Li, Xu , Shi, Hui , Ying, Zheng , Gao, Yongxiang , Ge, Honghua , Niu, Liwen and Teng, Maikun
Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The cleavage factor Im （CF Im）, consists of a 25 kDa subunit （CF Im25） and one of three larger subunits （CF Im59, CF Im68, CF Im72）, and is an essential protein complex for pre-mRNA 3＇-end cleavage and polyadenylation. It recognizes the upstream sequence of the poly（A） site in a sequence-dependent manner. Here we report the crystal structure of hum...
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Full title
Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3193493
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3193493
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2011.67
